Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197516
Type: Artigo de periódico
Title: Aquaporin 9 (aqp9) Localization In The Adult Dog Testis Excurrent Ducts By Immunohistochemistry.
Author: Domeniconi, Raquel Fantin
Orsi, Antonio Marcos
Justulin, Luis Antonio
Beu, Célia Cristina Leme
Felisbino, Sérgio Luis
Abstract: Aquaporins (AQPs) are small, intrinsic membrane proteins that are present in many cell types involved in fluid transport. AQP9 is a major apical water channel that is expressed throughout the efferent ducts, epididymis, and vas deferens, as well as in other regions of the human and rodent male reproductive tract. The target of this study was to examine the expression of AQP9 in epithelial cells in the adult dog efferent ducts, epididymis, and vas deferens. Samples of dog male reproductive tract comprising fragments of the testis; initial segment, caput, corpus, and cauda of the epididymis; and vas deferens were obtained from eight adult mongrel dogs. Immunohistochemistry and Western blotting procedures were used to show AQP9 localization and distribution. AQP9 expression was not detected either in dog seminiferous tubules or rete testis. However, apical labeling for AQP9 was detected in the different regions of epididymis and vas deferens, with the reaction being less intense in the caput epididymis. Thus, AQP9 is abundantly expressed in dog male reproductive tract, in which it is an important apical pathway for transmembrane flow of water and neutral solutes.
Subject: Animals
Aquaporins
Dogs
Epididymis
Epithelial Cells
Immunohistochemistry
Male
Testis
Vas Deferens
Rights: fechado
Identifier DOI: 10.1002/ar.20611
Address: http://www.ncbi.nlm.nih.gov/pubmed/17957752
Date Issue: 2007
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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