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http://repositorio.unicamp.br/jspui/handle/REPOSIP/197462
Type: | Artigo de periódico |
Title: | Platelet-rich Plasma May Not Provide Any Additional Effect When Associated With Guided Bone Regeneration Around Dental Implants In Dogs. |
Author: | de Vasconcelos Gurgel, Bruno César Gonçalves, Patrícia Furtado Pimentel, Suzana Peres Ambrosano, Gláucia Maria Bovi Nociti Júnior, Francisco Humberto Sallum, Enilson Antonio Casati, Marcio Zaffalon |
Abstract: | The aim of this study was to evaluate histometrically bone healing in surgically created dehiscence-type defects around titanium implants treated with an association of platelet-rich plasma (PRP) and guided bone regeneration (GBR). Ten male adult mongrel dogs were used, from which the three low premolars (P2, P3, P4) and the first molar were extracted. Three months after teeth extraction, two implant sites were bilaterally drilled, buccal bone dehiscences were created and four titanium implants were placed. Dehiscences were randomly assigned to the following groups: (1) PRP, (2) GBR, (3) PRP+GBR and (4) control. After 3 months, the animals were sacrificed and the implants and adjacent hard tissues were processed for undecalcified sections. Bone-to-implant contact (BIC), bone density within the limits of implant threads (BW), bone density (BD) and new bone area (BA) in a zone lateral to the implant corresponding to bone defects were obtained and measured. Intergroup analysis (two-way ANOVA -alpha=5%) demonstrated that when PRP was utilized,no differences were observed for all parameters (P>0.05). However, significant differences were observed for BIC and BW toward membrane-treated groups (P<0.05). Within the limits of this study, it was concluded that PRP does not exert additional effects on bone healing in bone defects created around dental implants and treated by GBR. |
Subject: | Animals Bone Density Bone Regeneration Dental Implants Dental Materials Dogs Guided Tissue Regeneration, Periodontal Male Mandible Mandibular Diseases Membranes, Artificial Osseointegration Osteogenesis Platelet-rich Plasma Polytetrafluoroethylene Random Allocation Surgical Wound Dehiscence Time Factors Titanium |
Citation: | Clinical Oral Implants Research. v. 18, n. 5, p. 649-54, 2007-Oct. |
Rights: | fechado |
Identifier DOI: | 10.1111/j.1600-0501.2007.01383.x |
Address: | http://www.ncbi.nlm.nih.gov/pubmed/17877464 |
Date Issue: | 2007 |
Appears in Collections: | Unicamp - Artigos e Outros Documentos |
Files in This Item:
File | Size | Format | |
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pmed_17877464.pdf | 1.13 MB | Adobe PDF | View/Open |
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