Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197378
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleSystemic Lupus Erythematosus And Pregnancy: Clinical Evolution, Maternal And Perinatal Outcomes And Placental Findings.pt_BR
dc.contributor.authorSurita, Fernanda Garanhani de Castropt_BR
dc.contributor.authorParpinelli, Mary Angelapt_BR
dc.contributor.authorYonehara, Emapt_BR
dc.contributor.authorKrupa, Fabianapt_BR
dc.contributor.authorCecatti, José Guilhermept_BR
unicamp.authorFernanda Garanhani de Castro Surita, Department of Obstetrics and Gynecology, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. surita@unicamp.brpt_BR
unicamp.author.externalMary Angela Parpinelli,pt
unicamp.author.externalEma Yonehara,pt
unicamp.author.externalFabiana Krupa,pt
unicamp.author.externalJosé Guilherme Cecatti,pt
dc.subjectAdolescentpt_BR
dc.subjectAdultpt_BR
dc.subjectCesarean Sectionpt_BR
dc.subjectEpidemiologic Methodspt_BR
dc.subjectFemalept_BR
dc.subjectFetal Growth Retardationpt_BR
dc.subjectHumanspt_BR
dc.subjectInfant, Low Birth Weightpt_BR
dc.subjectInfant, Newbornpt_BR
dc.subjectKidney Diseasespt_BR
dc.subjectLupus Erythematosus, Systemicpt_BR
dc.subjectLupus Nephritispt_BR
dc.subjectPlacentapt_BR
dc.subjectPre-eclampsiapt_BR
dc.subjectPregnancypt_BR
dc.subjectPregnancy Complicationspt_BR
dc.subjectPregnancy Outcomept_BR
dc.subjectPrenatal Carept_BR
dc.description.abstractSystemic lupus erythematosus is a chronic disease that is more frequent in women of reproductive age. The relationship between lupus and pregnancy is problematic: maternal and fetal outcomes are worse than in the general population, and the management of flare-ups is difficult during this period. The aim here was to compare the outcomes of 76 pregnancies in 67 women with lupus, according to the occurrence or absence of flare-ups. An observational cohort clinical study evaluating the evolution of pregnant women with lupus who were receiving care at the prenatal outpatient clinic, Centro de Atenção Integral à Saúde da Mulher, Universidade Estadual de Campinas (CAISM/Unicamp), between 1995 and 2002. Data were collected on a precoded form. The women were divided into two groups according to the occurrence or absence of flare-ups, as defined by the systemic lupus erythematosus disease activity index (SLEDAI). The presence or absence of flare-ups and renal involvement was considered to be the independent variable and the other results were dependent variables. Flare-ups occurred in 85.3% of cases, and were most significant when there was renal involvement. This was related to greater numbers of women with preeclampsia and poor perinatal outcome. Intrauterine growth restriction was more common in the women with active disease. Placental weight was significantly lower in the women with renal involvement. Flare-ups and renal involvement in lupus patients during pregnancy are associated with increased maternal and perinatal complications.en
dc.relation.ispartofSão Paulo Medical Journal = Revista Paulista De Medicinapt_BR
dc.relation.ispartofabbreviationSao Paulo Med Jpt_BR
dc.date.issued2007-Marpt_BR
dc.identifier.citationSão Paulo Medical Journal = Revista Paulista De Medicina. v. 125, n. 2, p. 91-5, 2007-Mar.pt_BR
dc.language.isoengpt_BR
dc.description.volume125pt_BR
dc.description.initialpage91-5pt_BR
dc.rightsabertopt_BR
dc.rights.holderpt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn1516-3180pt_BR
dc.identifier.doipt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/17625706pt_BR
dc.date.available2015-11-27T13:10:17Z-
dc.date.accessioned2015-11-27T13:10:17Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T13:10:17Z (GMT). No. of bitstreams: 1 pmed_17625706.pdf: 91901 bytes, checksum: 51e9c91a77e9a6684f0d494994218497 (MD5) Previous issue date: 2007en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197378-
dc.identifier.idPubmed17625706pt_BR
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