Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197313
Type: Artigo de periódico
Title: Cryosurgical Treatment Of Lentigo Maligna.
Author: de Moraes, Aparecida Machado
Pavarin, Lilian Bianchi
Herreros, Fernanda
de Aguiar Michelman, Fábia
Velho, Paulo Eduardo Neves Ferreira
de Souza, Elemir Macedo
Abstract: Lentigo maligna (LM) is a common melanocytic malignancy which requires therapy because of the risk of progression to invasive lentigo maligna melanoma which a much worse prognosis. 18 patients with clinical and histopathological diagnosis of LM were treated with cryosurgery. The patients were older Caucasians (mean age 59.5 years) and 11 were male. They were chosen for cryosurgery because the lesion posed a surgical challenge or the patient was not a good surgical candidate. They were treated with two freeze-thaw cycles of liquid nitrogen under local anesthesia in a single sitting. Lesions larger than 2 cm(2) were divided into smaller segments for freezing. The lesions resolved clinically in all cases, with no recurrence or metastasis detected during a mean follow-up of 75.5 months. Some patients developed hypopigmented scars. Cryosurgery with liquid nitrogen is an efficient, safe and in most cases aesthetically acceptable alternative method to treat LM.
Subject: Cryosurgery
Female
Humans
Hutchinson's Melanotic Freckle
Male
Middle Aged
Neoplasm Recurrence, Local
Skin Neoplasms
Treatment Outcome
Rights: fechado
Identifier DOI: 10.1111/j.1610-0387.2007.06331.x
Address: http://www.ncbi.nlm.nih.gov/pubmed/17537040
Date Issue: 2007
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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