Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197311
Type: Artigo de periódico
Title: Use Of The Levonorgestrel-releasing Intrauterine System In Women With Endometriosis, Chronic Pelvic Pain And Dysmenorrhea.
Author: Bahamondes, Luis
Petta, Carlos A
Fernandes, Arlete
Monteiro, Ilza
Abstract: This report is a review of the medical literature on the use of the levonorgestrel-releasing intrauterine system (LNG-IUS) in women with endometriosis, adenomyosis, cyclic pelvic pain and dysmenorrhea. A review was carried out using the MEDLINE and EMBASE databases to evaluate the use of LNG-IUS in women with endometriosis and adenomyosis. Nine studies were identified, only two of which were randomized clinical trials. One compared the insertion of LNG-IUS after surgery with expectant conduct and the other compared the use of the device with a GnRH analogue (GnRH-a). All studies reported an improvement in pelvic pain and dysmenorrhea, and a reduction in menstrual bleeding. One study found an improvement in the staging of the disease at 6 months of use, and the studies that evaluated the use of LNG-IUS in women with adenomyosis reported a reduction in uterine volume. Furthermore, the only study in which women were followed up for 3 years after insertion found improvement in pelvic pain at 12 months of use. However, there was no improvement after that period. The use of LNG-IUS is an alternative for the medical treatment of women suffering from endometriosis, adenomyosis, chronic pelvic pain or dysmenorrhea, but experience is limited and long-term studies are necessary to reach definitive conclusions. However, for women who do not wish to become pregnant, this device offers the possibility of at least 5 years of treatment following one single intervention.
Subject: Dysmenorrhea
Endometriosis
Female
Humans
Intrauterine Devices, Medicated
Levonorgestrel
Pelvic Pain
Progestins
Randomized Controlled Trials As Topic
Rights: fechado
Identifier DOI: 10.1016/j.contraception.2006.12.008
Address: http://www.ncbi.nlm.nih.gov/pubmed/17531605
Date Issue: 2007
Appears in Collections:Unicamp - Artigos e Outros Documentos

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