Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/197276
Type: Artigo de periódico
Title: Poly (epsilon-caprolactone)/propolis Extract: Microencapsulation And Antibacterial Activity Evaluation.
Author: Durán, N
Marcato, P D
Buffo, C M S
De Azevedo, M M M
Esposito, E
Abstract: Spherical and homogenous microparticles of poly(epsilon-caprolactone) (PCL), containing propolis were prepared by the emulsification-solvent evaporation technique. Using this method of preparation, a solid formulation of propolis, free of ethanol and suitable for manipulation and storage, was obtained from an ethanolic extract of propolis. The incorporation efficiency of propolis in the microparticles was almost 30% and around 60% of the substance was released in 48 h. In vitro propolis microparticles exhibited similar halo zones in the Petri plate test against Streptococcus mutans (GS5) with a 10-fold lower concentration than the free propolis extract showing that the encapsulated propolis in microparticles is more efficient as antibiotic.
Subject: Anti-infective Agents
Bacteria
Caproates
Capsules
Chemistry, Pharmaceutical
Drug Compounding
Kinetics
Lactones
Microbial Sensitivity Tests
Particle Size
Propolis
Solubility
Solvents
Streptococcus Mutans
Surface-active Agents
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/17484285
Date Issue: 2007
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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