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Type: Artigo de periódico
Title: Sol-gel Molecular Imprinted Ormosil For Solid-phase Extraction Of Methylxanthines.
Author: da Costa Silva, Raquel Gomes
Augusto, Fabio
Abstract: A organically modified molecularly imprinted silica (MIS), selective for methylxanthines, was prepared using a simple sol-gel procedure. Caffeine was used as template; 3-aminopropyltrimethoxysilane (APTMS) as functional monomer and tetraethyl orthosilicate (TEOS) as reticulating agent. The material was packed on solid-phase extraction (SPE) cartridges and evaluated with aqueous test samples, natural water and human urine; a quantitative method for methylxanthines in water, using SPE cartridges packed with the MIS coupled with HPLC-UV was developed. The MIS was highly specific for methylxanthines, with an imprinting factor of (20.5+/-1.9). The analytical method resulted in detection limits of 85 microgL(-1) for theobromine, 44 microgL(-1) for theophylline and 53 microgL(-1) for caffeine.
Subject: Chromatography, High Pressure Liquid
Phase Transition
Sensitivity And Specificity
Spectrophotometry, Infrared
Ultraviolet Rays
Rights: fechado
Identifier DOI: 10.1016/j.chroma.2006.03.073
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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