Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: [congenital Adrenal Hyperplasia Due To 21-hydroxylase Deficiency: Final Height In 27 Patients With The Classical Form].
Author: Lemos-Marini, Sofia H V
Guerra-Júnior, Gil
Morcillo, André M
Baptista, Maria Tereza M
Silva, Luciana O
Maciel-Guerra, Andréa T
Abstract: To determine final height (FH) in congenital adrenal hyperplasia (CAH) patients and investigate conditions allowing better height outcome. 13 salt-wasting (SW) and 14 simple virilizing (SV) patients were studied. FH and target height (TH) were transformed into standard deviation score (z). Data were analyzed according to sex, clinical form, age at treatment onset and length of treatment before attaining FH. zFH (n = 27) was -1.57 +/- 1.01. FH (-1.50 +/- 1.03) was below TH (-0.78 +/- 0.84) (n = 25, p < 0.001). FH has not differed according to sex, clinical form and age at therapy onset although there was a trend towards better FH in SW patients and in early treated cases; there was significant difference (p = 0.018) between patients treated for less than 5 years (-2.49 +/- 1.03) and those accompanied longer than 10 years (-1.21 +/- 0.88) before attaining FH. There was a FH impairment and adult height improvement seems to depend mainly on early diagnosis and treatment.
Subject: Adolescent
Adrenal Hyperplasia, Congenital
Analysis Of Variance
Body Height
Child, Preschool
Follow-up Studies
Infant, Newborn
Statistics, Nonparametric
Steroid 21-hydroxylase
Time Factors
Treatment Outcome
Citation: Arquivos Brasileiros De Endocrinologia E Metabologia. v. 49, n. 6, p. 902-7, 2005-Dec.
Rights: aberto
Identifier DOI: /S0004-27302005000600008
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_16544012.pdf69.75 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.