Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/196686
Type: Artigo de periódico
Title: [congenital Adrenal Hyperplasia Due To 21-hydroxylase Deficiency: Final Height In 27 Patients With The Classical Form].
Author: Lemos-Marini, Sofia H V
Guerra-Júnior, Gil
Morcillo, André M
Baptista, Maria Tereza M
Silva, Luciana O
Maciel-Guerra, Andréa T
Abstract: To determine final height (FH) in congenital adrenal hyperplasia (CAH) patients and investigate conditions allowing better height outcome. 13 salt-wasting (SW) and 14 simple virilizing (SV) patients were studied. FH and target height (TH) were transformed into standard deviation score (z). Data were analyzed according to sex, clinical form, age at treatment onset and length of treatment before attaining FH. zFH (n = 27) was -1.57 +/- 1.01. FH (-1.50 +/- 1.03) was below TH (-0.78 +/- 0.84) (n = 25, p < 0.001). FH has not differed according to sex, clinical form and age at therapy onset although there was a trend towards better FH in SW patients and in early treated cases; there was significant difference (p = 0.018) between patients treated for less than 5 years (-2.49 +/- 1.03) and those accompanied longer than 10 years (-1.21 +/- 0.88) before attaining FH. There was a FH impairment and adult height improvement seems to depend mainly on early diagnosis and treatment.
Subject: Adolescent
Adrenal Hyperplasia, Congenital
Analysis Of Variance
Body Height
Child
Child, Preschool
Female
Follow-up Studies
Glucocorticoids
Humans
Infant
Infant, Newborn
Male
Mineralocorticoids
Prognosis
Statistics, Nonparametric
Steroid 21-hydroxylase
Time Factors
Treatment Outcome
Rights: aberto
Identifier DOI: /S0004-27302005000600008
Address: http://www.ncbi.nlm.nih.gov/pubmed/16544012
Date Issue: 2005
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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