Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/196613
Type: Artigo de periódico
Title: Human Cryptococcosis: Relationship Of Environmental And Clinical Strains Of Cryptococcus Neoformans Var. Neoformans From Urban And Rural Areas.
Author: Delgado, A C N
Taguchi, H
Mikami, Y
Myiajy, M
Villares, M C B
Moretti, M L
Abstract: Forty-five clinical and 55 environmental strains of Cryptococcus neoformans var. neoformans from São Paulo, Brazil, were tested for their susceptibilities to amphotericin B, fluconazole, itraconazole, and flucytosine by the broth microdilution method according to the National Committee of Clinical Laboratory Standards guidelines. Electrophoretic karyotypes analysis by counter-clamped homogeneous electrophoresis was used to compare their genetic relatedness. Molecular typing revealed three clinical profiles very similar to two environmental profiles and an identical environmental and clinical profile. The results showed that human cryptococcosis can be acquired from environmental strains, which had similar minimum inhibitory concentration values to clinical strains, for antifungal agents.
Subject: Animals
Antifungal Agents
Brazil
Columbidae
Cryptococcosis
Cryptococcus Neoformans
Dna, Fungal
Electrophoresis, Gel, Pulsed-field
Humans
Karyotyping
Microbial Sensitivity Tests
Rural Population
Urban Population
Rights: fechado
Identifier DOI: 10.1007/s11046-004-9618-4
Address: http://www.ncbi.nlm.nih.gov/pubmed/15750727
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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