Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/196422
Type: Artigo de periódico
Title: The Prima Donna Of Epigenetics: The Regulation Of Gene Expression By Dna Methylation.
Author: Santos, K F
Mazzola, T N
Carvalho, H F
Abstract: This review focuses on the mechanisms of DNA methylation, DNA methylation pattern formation and their involvement in gene regulation. Association of DNA methylation with imprinting, embryonic development and human diseases is discussed. Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in transgenerational carcinogenesis, in memory formation and behavior establishment are brought about as mechanisms based on the cellular memory of gene expression patterns.
Subject: Animals
Cell Differentiation
Cpg Islands
Dna Methylation
Epigenesis, Genetic
Gene Expression Regulation
Gene Silencing
Humans
Inheritance Patterns
Memory
Neoplasms
Rights: aberto
Identifier DOI: /S0100-879X2005001000010
Address: http://www.ncbi.nlm.nih.gov/pubmed/16172746
Date Issue: 2005
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

Files in This Item:
File SizeFormat 
pmed_16172746.pdf496.76 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.