Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: Increasing Seroprevalence Of Human Herpesvirus 8 (hhv-8) With Age Confirms Hhv-8 Endemicity In Amazon Amerindians From Brazil.
Author: Cunha, A M G
Caterino-de-Araujo, A
Costa, S C B
Santos-Fortuna, E
Boa-Sorte, N C A
Gonçalves, M S
Costa, F F
Galvão-Castro, B
Abstract: Human herpesvirus 8 (HHV-8) seroprevalences were determined in two isolated Amazon Amerindian tribes, according to age, gender and familial aggregation. Plasma and serum samples obtained from 982 Amazon Amerindians (664 Tiriyó and 318 Waiampi) were tested for antibodies against lytic and latent HHV-8 antigens by using 'in-house' immunofluorescence assays. Overall, HHV-8 seroprevalence was 56.8 % (57.4 % in the Tiriyó tribe and 55.7 % in the Waiampi tribe). Seroprevalence was independent of gender and increased linearly with age: it was 35.0 % among children aged 2-9 years, 51.4 % in adolescents (10-19 years), 72.9 % in adults and 82.3 % in adults aged >50 years. Interestingly, 44.4 % of children under 2 years of age were HHV-8-seropositive. No significant differences in seroprevalence between tribes and age groups were detected. It is concluded that HHV-8 is hyperendemic in Brazilian Amazon Amerindians, with vertical and horizontal transmission during childhood, familial transmission and sexual contact in adulthood contributing to this high prevalence in these isolated populations.
Subject: Adolescent
Age Distribution
Antibodies, Viral
Antigens, Viral
Child, Preschool
Endemic Diseases
Ethnic Groups
Herpesviridae Infections
Herpesvirus 8, Human
Indians, South American
Middle Aged
Seroepidemiologic Studies
Sex Distribution
Citation: The Journal Of General Virology. v. 86, n. Pt 9, p. 2433-7, 2005-Sep.
Rights: fechado
Identifier DOI: 10.1099/vir.0.81087-0
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_16099900.pdf295.64 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.