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Type: Artigo de periódico
Title: Human Herpesvirus Type 6 And Type 1 Infection Increases Susceptibility To Nonmelanoma Skin Tumors.
Author: Leite, Janaína Luisa
Stolf, Hamilton Ometto
Reis, Nilton Avila
Ward, Laura S
Abstract: In order to investigate herpesvirus (HHV) role in the susceptibility to skin cancer, we compared HHV6 and HHV1 incidence in DNA samples extracted from 120 lesions and 41 normal skin tissues. HHV6 (31.7%) and HHV1 (23.8%) were detected more frequently in skin cancer than in control individuals (14.6 and 5%, respectively) (P=0.0391 and P=0.00094, respectively). The risk of presenting basal cell carcinomas (BCC) was more than 3 times higher for HHV-6 infected patients (OR=3.182; 95% CI: 1.125-8.997). The risk for HHV-1 infected individuals of presenting BCC and squamous cell carcinomas was increased 8 and 6 times, respectively (OR=8.125; 95% CI: 1.735-38.043 and OR=6.290; 95% CI: 1.283-30.856, respectively).
Subject: Adolescent
Aged, 80 And Over
Carcinoma, Basal Cell
Carcinoma, Squamous Cell
Case-control Studies
Dna, Viral
Herpes Simplex
Herpesvirus 1, Human
Herpesvirus 6, Human
Middle Aged
Odds Ratio
Polymerase Chain Reaction
Risk Factors
Roseolovirus Infections
Skin Neoplasms
Rights: fechado
Identifier DOI: 10.1016/j.canlet.2004.11.010
Date Issue: 2005
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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