Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/196198
Type: Artigo de periódico
Title: Postexposure Prophylaxis After Sexual Assaults: A Prospective Cohort Study.
Author: Garcia, Márcia Teixeira
Figueiredo, Rosely Moralez
Moretti, Maria Luiza
Resende, Máriangela Ribeiro
Bedoni, Aloásio J
Papaiordanou, Priscila Maria O
Abstract: The objective of this study was to evaluate HIV postexposure prophylaxis (PEP) protocol in rape victims. The victims were assigned to 1 of 3 categories, according to the severity of exposure (I-low, II-moderate, III-high). HIV PEP was provided to victims in groups II (Zdv + 3TC) and III (Zdv + 3TC + PI) until 72 hours after exposure. The follow-up was 6 months. From May 1997 to October 2001, 347 victims were attended. PEP was offered to 278 victims (141 in group II and 137 in group III). Side effects were more common in group III (P <0.01). No seroconversion was diagnosed in the 180 victims that completed the follow-up. Univariate analysis showed that the schooling level, knowledge of the aggressor's HIV status, and the use of PEP were associated with compliance. Triple therapy was associated with side effects, which suggested that drug regimes should be reviewed. The variables related to a high risk of HIV transmission were also significant for compliance.
Subject: Adolescent
Adult
Aged
Anti-hiv Agents
Brazil
Child
Child, Preschool
Cohort Studies
Drug Administration Schedule
Female
Hiv Infections
Humans
Indinavir
Lamivudine
Male
Middle Aged
Nelfinavir
Patient Compliance
Prospective Studies
Rape
Sexually Transmitted Diseases
Zidovudine
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/15788918
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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