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Type: Artigo de periódico
Title: Genetic Variation And Relationships At Six Vntr Loci In Two Distinct Sample Populations In Brazil.
Author: Ramos, C F
Magna, L A
de Mello, M P
Silva, R
de Moura-Neto, R S
Abstract: The Brazilian population has been the focus of intensive genetic study due to admixture characteristics whereas there are few reports on the variability of VNTR loci in Brazil. The aim of this study was to analyse genetic parameters in sample populations from two geographically distant regions: São Luis City, in Maranhão State and Campinas City, in São Paulo State. We investigated if distinct colonization influences could produce detectable differences in genetic background. DNA samples from peripheral drained blood were obtained from unrelated individuals who underwent paternity testing. Allelic variation in six VNTR loci (D2S44, D4S139, D5S110, D8S358, DI0S28 and D17S79) was evaluated. The results were compared to reference databases available for general Latin-derived European and African-American populations as well as for other Brazilian groups. This study reveals that forensic population parameters did not show differences among regions, although we detected admixture values varying between the south-east and north-east of Brazil. Differences between the two samples are probably due to different admixture proportions of European- and African-derived alleles in each region: both populations are in Hardy Weinberg equilibrium. In addition, the allelic frequency for all loci, in both populations, can be used as database for forensic purposes.
Subject: African Continental Ancestry Group
Blotting, Southern
European Continental Ancestry Group
Gene Frequency
Genetic Variation
Genetics, Population
Minisatellite Repeats
Citation: Annals Of Human Biology. v. 31, n. 6, p. 660-8
Rights: fechado
Appears in Collections:Unicamp - Artigos e Outros Documentos

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