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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleClinical Implications Of Migraine In Systemic Lupus Erythematosus: Relation To Cumulative Organ Damage.pt_BR
dc.contributor.authorAppenzeller, Spt_BR
dc.contributor.authorCostallat, L T Lpt_BR
unicamp.authorS Appenzeller, Unit of Rheumatology, Department of Internal Medicine State University of Campinas Faculty of Medical Sciences, Campinas, Brazil. appenzel@unicamp.brpt_BR
unicamp.author.externalL T L Costallat,pt
dc.subjectAdolescentpt_BR
dc.subjectAdultpt_BR
dc.subjectAntibodies, Antiphospholipidpt_BR
dc.subjectArthritis, Rheumatoidpt_BR
dc.subjectComorbiditypt_BR
dc.subjectHumanspt_BR
dc.subjectLupus Erythematosus, Systemicpt_BR
dc.subjectMalept_BR
dc.subjectMiddle Agedpt_BR
dc.subjectMigraine Disorderspt_BR
dc.subjectRaynaud Diseasept_BR
dc.description.abstractThe aim of this study was to determine the clinical implications of migraine in systemic lupus erythematosus (SLE) using the cumulative organ damage scores (SLICC-DI). Eighty SLE, 40 rheumatoid arthritis (RA) patients and 40 controls (non SLE, nor RA out-patients), all women, were included. Migraine was defined according to the International Headache Society (IHS) criteria for neuropsychiatric SLE. Disease activity was measured by MEX-SLEDAI and cumulative organ damage by SLICC-DI. Statistics were obtained by Chi-square and Fischer's exact tests. anova was used for comparing means. Migraine was identified in 42.5% of SLE patients, compared to 12.5% of RA patients (P < 0.05) and 10.0% (P < 0.05) in the control group. In the SLE group, a significant association between migraine and Raynaud's phenomenon (P = 0.003, OR = 10.1; 95%CI 2.9-35) and antiphospholipid antibodies (P = 0.0012; OR = 7.5; 95%CI 2.5-22.9) was noted. SLE patients with active migraine had higher MEX-SLEDAI scores than SLE patients without migraine. SLE patients with past history of migraine had significantly higher SLICC scores than SLE patients without migraine. History of migraine was associated with greater organ damage. Active migraine was associated with higher disease activity, antiphospholipid antibodies and worsening of Raynaud's phenomenon. The increased cumulative organ damage in SLE patients with past history of migraine justifies the routine evaluation of migraine in clinical practice.en
dc.relation.ispartofCephalalgia : An International Journal Of Headachept_BR
dc.relation.ispartofabbreviationCephalalgiapt_BR
dc.date.issued2004-Decpt_BR
dc.identifier.citationCephalalgia : An International Journal Of Headache. v. 24, n. 12, p. 1024-30, 2004-Dec.pt_BR
dc.language.isoengpt_BR
dc.description.volume24pt_BR
dc.description.firstpage1024-30pt_BR
dc.rightsfechadopt_BR
dc.rights.holderpt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0333-1024pt_BR
dc.identifier.doi10.1111/j.1468-2982.2004.00785.xpt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/15566416pt_BR
dc.date.available2015-11-27T12:58:36Z-
dc.date.accessioned2015-11-27T12:58:36Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:58:36Z (GMT). No. of bitstreams: 1 pmed_15566416.pdf: 74113 bytes, checksum: 3439fa584d53c106c4b3b81af169909b (MD5) Previous issue date: 2004en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/196041-
dc.identifier.idPubmed15566416pt_BR
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