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Type: Artigo de periódico
Title: Enantioselective Syntheses Of (r)- And (s)-argentilactone And Their Cytotoxic Activities Against Cancer Cell Lines.
Author: de Fatima, Angelo
Kohn, Luciana Konecny
Antônio, Márcia Aparecida
de Carvalho, João Ernesto
Pilli, Ronaldo Aloise
Abstract: Concise total syntheses of (R)- and (S)-argentilactone have been developed via enantioselective catalytic allylation (ECA) and ring-closing metathesis pathways (four steps, 39% overall yield and 82-84% ee) from 2-octynal and their in vitro activity against cancer cells is described.
Subject: Antineoplastic Agents
Cell Line, Tumor
Citation: Bioorganic & Medicinal Chemistry. v. 12, n. 20, p. 5437-42, 2004-Oct.
Rights: fechado
Identifier DOI: 10.1016/j.bmc.2004.07.044
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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