Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/195939
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleFrequency Of The 35delg Mutation In The Gjb2 Gene In Samples Of European, Asian, And African Brazilians.pt_BR
dc.contributor.authorOliveira, C Apt_BR
dc.contributor.authorAlexandrino, Fpt_BR
dc.contributor.authorAbe-Sandes, Kpt_BR
dc.contributor.authorSilva, W Apt_BR
dc.contributor.authorMaciel-Guerra, A Tpt_BR
dc.contributor.authorMagna, L Apt_BR
dc.contributor.authorSartorato, E Lpt_BR
unicamp.authorC A Oliveira, Centro de Biologia Molecular e Engenharia Genética, Universidade Estadual de Campinas, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil.pt_BR
unicamp.author.externalF Alexandrino,pt
unicamp.author.externalK Abe-Sandes,pt
unicamp.author.externalW A Silva,pt
unicamp.author.externalA T Maciel-Guerra,pt
unicamp.author.externalL A Magna,pt
unicamp.author.externalE L Sartorato,pt
dc.subjectAfricapt_BR
dc.subjectAsiapt_BR
dc.subjectBrazilpt_BR
dc.subjectConnexinspt_BR
dc.subjectDna Mutational Analysispt_BR
dc.subjectDeafnesspt_BR
dc.subjectEuropept_BR
dc.subjectHumanspt_BR
dc.subjectPolymerase Chain Reactionpt_BR
dc.description.abstractMutations in the GJB2 gene are a major cause of congenital deafness. One specific mutation, the 35delG mutation, has accounted for most of the GJB2 mutations detected in European populations and is one of the most frequent disease mutations identified so far. We evaluated the frequency of the 35delG mutation in DNA samples from Brazilians of European, Asian, and African ancestry. All DNA samples were screened for the 35delG mutation using an allele-specific PCR. This study shows that the frequency of a common mutation (35delG) is significantly lower in non-European populations.en
dc.relation.ispartofHuman Biologypt_BR
dc.relation.ispartofabbreviationHum. Biol.pt_BR
dc.date.issued2004-Aprpt_BR
dc.identifier.citationHuman Biology. v. 76, n. 2, p. 313-6, 2004-Apr.pt_BR
dc.language.isoengpt_BR
dc.description.volume76pt_BR
dc.description.firstpage313-6pt_BR
dc.rightsfechadopt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0018-7143pt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/15359540pt_BR
dc.date.available2015-11-27T12:58:26Z-
dc.date.accessioned2015-11-27T12:58:26Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:58:26Z (GMT). No. of bitstreams: 1 pmed_15359540.pdf: 173193 bytes, checksum: 1154e7bf41ca5a69e60dcc396bfcd96f (MD5) Previous issue date: 2004en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195939-
dc.identifier.idPubmed15359540pt_BR
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_15359540.pdf169.13 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.