Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/195784
Type: Artigo de periódico
Title: Suppression Of Dioxin Mediated Aryl Hydrocarbon Receptor Transformation By Ethanolic Extracts Of Propolis.
Author: Park, Yong K
Fukuda, Itsuko
Ashida, Hitoshi
Nishiumi, Shin
Guzman, Julio Paredes
Sato, Helia H
Pastore, Glaucia M
Abstract: Present study demonstrated that the ethanolic extracts of propolis containing higher concentrations of flavonoids suppressed 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced aryl hydrocarbon receptor transformation in a dose-dependent manner. The IC(50) values of propolis group 3 and group 12 were 1.2 and 3.6 microg/ml, respectively, indicating that propolis showed stronger antagonistic effects as compared with vegetable extracts.
Subject: Animals
Dose-response Relationship, Drug
Ethanol
Flavonoids
Fruit
Gene Expression Regulation
Inhibitory Concentration 50
Plant Extracts
Propolis
Rats
Receptors, Aryl Hydrocarbon
Suppression, Genetic
Tetrachlorodibenzodioxin
Vegetables
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/15118327
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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