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Type: Artigo de periódico
Title: Suppression Of Dioxin Mediated Aryl Hydrocarbon Receptor Transformation By Ethanolic Extracts Of Propolis.
Author: Park, Yong K
Fukuda, Itsuko
Ashida, Hitoshi
Nishiumi, Shin
Guzman, Julio Paredes
Sato, Helia H
Pastore, Glaucia M
Abstract: Present study demonstrated that the ethanolic extracts of propolis containing higher concentrations of flavonoids suppressed 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced aryl hydrocarbon receptor transformation in a dose-dependent manner. The IC(50) values of propolis group 3 and group 12 were 1.2 and 3.6 microg/ml, respectively, indicating that propolis showed stronger antagonistic effects as compared with vegetable extracts.
Subject: Animals
Dose-response Relationship, Drug
Gene Expression Regulation
Inhibitory Concentration 50
Plant Extracts
Receptors, Aryl Hydrocarbon
Suppression, Genetic
Citation: Bioscience, Biotechnology, And Biochemistry. v. 68, n. 4, p. 935-8, 2004-Apr.
Rights: fechado
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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