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Type: Artigo de periódico
Title: Elastic Properties Of Stored Red Blood Cells From Sickle Trait Donor Units.
Author: Brandão, M M
Saad, S T O
Cezar, C L
Fontes, A
Costa, F F
Barjas-Castro, M L
Abstract: Red blood cells (RBCs) from patients with sickle cell disease present reduced deformability. The aim of this study was to analyse the elasticity of stored RBCs from patients with the sickle cell trait (AS). The cell elasticity was studied, using laser optical tweezers, on storage days 1, 14, 21, 28 and 35. The elasticity of RBC from AS units stored for 1, 14 and 21 days was significantly greater compared with that of control RBC cells stored for the same time-period. More than 30% of the cells from AS units stored for 28 or 35 days were very rigid and escaped from the optical trap. RBCs became rigid during storage, suggesting that haemoglobin S might compromise the cell elasticity.
Subject: Blood Donors
Blood Preservation
Case-control Studies
Erythrocyte Deformability
Erythrocytes, Abnormal
In Vitro Techniques
Sickle Cell Trait
Time Factors
Rights: fechado
Identifier DOI: 
Date Issue: 2003
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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