Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/195478
Type: Artigo de periódico
Title: Serum High-density Lipoprotein (hdl) Inhibits In Vitro Enterohemolysin (ehly) Activity Produced By Enteropathogenic Escherichia Coli.
Author: Figueirêdo, Patricia M S
Catani, Cleide F
Yano, Tomomasa
Abstract: Enterohemolysin (EHly) produced by Escherichia coli shows hemolytic activity towards washed erythrocytes from different animal species on blood agar plates. It has been shown recently that EHly activity is inhibited by normal mammalian serum and by cholesterol in vitro. Plasma lipoproteins can interact with bacterial toxins, such as endotoxin, to reduce their toxicity. In this work, we examine the ability of human purified chylomicrons, very low-density lipoproteins, intermediate-density, low-density and high-density lipoproteins, to inhibit the hemolytic activity of EHly. Our results show that these lipoproteins are hemolysin inactivators, and that high-density lipoprotein is the most potent inhibitor of enterohemolytic activity.
Subject: Cholesterol, Hdl
Erythrocytes
Escherichia Coli
Escherichia Coli Proteins
Hemolysin Proteins
Humans
In Vitro Techniques
Citation: Fems Immunology And Medical Microbiology. v. 38, n. 1, p. 53-7, 2003-Aug.
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/12900055
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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