Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/195365
Type: Artigo de periódico
Title: Effect Of The Crude Extract Of Vernonia Polyanthes Less. On Blood Pressure And Renal Sodium Excretion In Unanesthetized Rats.
Author: Romanezi da Silveira, R
Foglio, M A
Gontijo, J A R
Abstract: This study evaluated the effect of oral crude Vernonia polyanthes Less. hydroalcoholic extract administration (CHE, 0.5 and 1.0 g/kg body wt., daily for 7 days) on arterial blood pressure and renal sodium excretion in conscious rats. CHE administration decreased arterial blood pressure dose-dependently followed by a significant rise in creatinine clearance and a fall in fractional post-proximal sodium excretion was compared to the control group. These results suggest that blood pressure decrease induced by the oral crude Vernonia hydroalcoholic extract may be blunted by reduction of the post-proximal renal sodium excretion. Thus, the present study shows that Vernonia extract is a potential vasodilatation agent in normotensive rats without any effects on renal tubule autoregulation mechanisms.
Subject: Animals
Blood Pressure
Creatinine
Male
Plant Extracts
Plant Leaves
Rats
Rats, Wistar
Sodium
Vernonia
Rights: fechado
Identifier DOI: 10.1078/094471103321659825
Address: http://www.ncbi.nlm.nih.gov/pubmed/12725565
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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