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Type: Artigo de periódico
Title: Cytotoxic Withanolides From Acnistus Arborescens.
Author: Minguzzi, Sandro
Barata, Lauro E S
Shin, Young Geun
Jonas, Patrick F
Chai, Hee Byung
Park, Eun Jung
Pezzuto, John M
Cordell, Geoffrey A
Abstract: Three cytotoxic withanolides, two with new structures, were isolated from the leaves of Acnistus arborescens and their structures determined by a combination of 1D and 2D NMR, mass spectral, and molecular modeling studies. Dereplication analysis of the ethyl ether extract was useful for evaluating the components showing significant cytotoxic activity.
Subject: Animals
Antineoplastic Agents
Cell Survival
Enzyme Induction
Epoxy Compounds
Magnetic Resonance Spectroscopy
Nad(p)h Dehydrogenase (quinone)
Tumor Cells, Cultured
Rights: fechado
Identifier DOI: 
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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