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Type: Artigo de periódico
Title: Bone Density Around Titanium Implants May Be Influenced By Intermittent Cigarette Smoke Inhalation: A Histometric Study In Rats.
Author: Nociti, Francisco Humberto
César, Neto João Batista
Carvalho, Marcelo Diniz
Sallum, Enilson Antonio
Abstract: This study investigated the influence of cigarette smoke on bone healing around titanium implants placed in rats. After administration of anesthesia, the tibia surface was exposed and screw-shaped titanium implants (4.0 mm in length and 2.2 mm in diameter) were placed bilaterally (1 each side). The animals (n = 32) were randomly assigned to either group 1 (control, n = 18) or group 2 (intermittent cigarette smoke inhalation, n = 14). After 60 days, the animals were sacrificed and undecalcified sections obtained. Bone density (the proportion of mineralized bone in a 500-microm-wide zone lateral to the implant) was measured in the cortical (zone A) and cancellous bone (zone B) areas. In zone A, a slight difference in bone density was noted between the groups (96.18% +/- 1.08% and 95.38 +/- 1.17% in groups 1 and 2, respectively; P > .05) but was not statistically significant. In contrast, bone density was significantly decreased in zone B in the animals that were exposed to cigarette smoke (17.57 +/- 6.45% and 11.30 +/- 6.81% for groups 1 and 2, respectively; P < .05). Whether different results would be observed if animals were exposed to cigarette smoke for a longer period of time and/or before implant placement remains to be investigated. Although intermittent cigarette smoke exposure may not seriously affect cortical bone density, it may jeopardize bone quality around titanium implants in the cancellous bone area.
Subject: Animals
Bone Density
Dental Implants
Random Allocation
Rats, Wistar
Statistics, Nonparametric
Time Factors
Tobacco Smoke Pollution
Wound Healing
Citation: The International Journal Of Oral & Maxillofacial Implants. v. 17, n. 3, p. 347-52
Rights: fechado
Appears in Collections:Unicamp - Artigos e Outros Documentos

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