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|Type:||Artigo de periódico|
|Title:||The Effect Of Different Doses Of Propofol On Tracheal Intubating Conditions Without Muscle Relaxant In Children.|
|Author:||De Fátima De Assunção Braga, A|
Da Silva Braga, F S
Potério, G M
Filier, P R
|Abstract:||Situations may occur in anaesthetic practice where the use of neuromuscular blocking drugs is unsuitable or contraindicated. We investigated the use of propofol given 5 min after fentanyl to permit endotracheal intubation in children. We studied the intubating conditions and cardiovascular parameters in 60 ASA I and II children. Intravenous midazolam (0.1 mg kg(-1)) was given as premedication 5 min before the induction of anaesthesia. The children received different doses of propofol (group I, 2.5 mg kg(-1); group II, 3.0 mg kg(-1); group III, 3.5 mg kg-1) preceded by fentanyl (3.0 microg kg(-1)) given 5 min earlier. No neuromuscular blocking agents were administered. The intubating conditions were assessed using a four-point scoring system based on the degree of difficulty of laryngoscopy, the position of vocal cords and the intensity of coughing. Tracheal intubating conditions were adequate in 20% of the patients in group I, in 75% of the patients in group II and in 80% of the patients in group III (P < 0.05 for group I vs. groups II and III). Haemodynamic changes were not significantly different between the groups. Propofol (3.0 mg kg(-1)) preceded by fentanyl (3.0 microg kg(-1)) was adequate for the induction of anaesthesia in children and provided adequate tracheal intubating conditions without significant haemodynamic changes. This method represents a useful alternative technique for tracheal intubation when neuromuscular blocking drugs are contraindicated or should be avoided.|
Dose-response Relationship, Drug
Hypnotics And Sedatives
|Citation:||European Journal Of Anaesthesiology. v. 18, n. 6, p. 384-8, 2001-Jun.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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