Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/195016
Type: Artigo de periódico
Title: Selective Trace Level Analysis Of Phenolic Compounds In Water By Flow Injection Analysis--membrane Introduction Mass Spectrometry.
Author: Alberici, R M
Sparrapan, R
Jardim, W F
Eberlin, M N
Abstract: Flow injection analysis coupled with membrane introduction mass spectrometry (FIA-MIMS) with on-line derivatization is shown to allow fast, accurate, nearly interference-free, and sensitive (low microgram/L) quantitation of phenolic compounds in water. On-line FIA derivatization of the phenolic compounds is performed by acetic anhydride acetylation in a K2CO3-buffered alkaline medium. The phenol acetates so formed efficiently permeate a silicone membrane and are directly transferred to the mass spectrometer, in which they are analyzed with selectivity and high sensitivity via selected ion monitoring. FIA-MIMS analysis was performed for aqueous solutions of phenol, 2-methylphenol, 4-chlorophenol, 4-chloro-3-methylphenol, 2,4-dichlorophenol, and 2,4,6-trichlorophenol, and detection limits in the 0.5-20 micrograms/L (ppb) range were observed for an analytical frequency of six samples/h. FIA-MIMS for phenolic compound analysis is considerably less time-consuming and labor intensive than most chromatographic methods based on liquid-liquid extraction and preconcentration procedures and is therefore applicable for on-line and in-situ monitoring of phenols in wastewaters and in the environment. FIA-MIMS employing acetic anhydride derivatization is also virtually free of interferences since it combines chemical, membrane, and enhanced MS selectivity; hence quantitation of phenolic compounds can be performed in the presence of congeners.
Subject: Acetates
Environmental Monitoring
Mass Spectrometry
Phenols
Sensitivity And Specificity
Water Pollutants, Chemical
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/11393991
Date Issue: 2001
Appears in Collections:Unicamp - Artigos e Outros Documentos

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