Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194977
Type: Artigo de periódico
Title: Morphological And Intracellular Alterations Induced By Cytotoxin Vt2y Produced By Escherichia Coli Isolated From Chickens With Swollen Head Syndrome.
Author: Salvadori, M R
Yamada, A T
Yano, T
Abstract: Recently, a novel verocytotoxin named VT2y was described which belongs to the STx family and is produced by Escherichia coli isolated from domestic poultry with swollen head syndrome (SHS). The VT2y toxin induced apoptosis in Vero, HeLa, CHO, CEF (primary chicken embryo fibroblast) and PCK (primary chicken kidney) cell lines. Morphological evidence (nuclear shrinkage, chromatin condensation and blebbing of the plasma membrane) of apoptosis could be distinguished in 15 min and was maximal at 1 h after treatment with VT2y. This was confirmed by the terminal dUTP nick-end-labeling (TUNEL) method.
Subject: Animals
Apoptosis
Cho Cells
Cell Line
Cercopithecus Aethiops
Chickens
Cricetinae
Escherichia Coli
Escherichia Coli Infections
Hela Cells
Humans
In Situ Nick-end Labeling
Neutral Red
Poultry Diseases
Shiga Toxin 2
Vero Cells
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/11287150
Date Issue: 2001
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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