Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194969
Type: Artigo de periódico
Title: Cytotoxin Production In Phytopathogenic And Entomopathogenic Serratia Marcescens.
Author: Escobar, M M
Carbonell, G V
Beriam, L O
Siqueira, W J
Yano, T
Abstract: In this work, culture filtrates of entomopathogenic and phytopathogenic Serratia marcescens strains induced cytotoxic effects on CHO, Vero and HEp-2 cell lines. Morphological changes on sensitive cells were characterized by cell rounding and detachment as soon as 30 min of incubation, culminating in cell death after 24 h. The cytotoxic effect was completely neutralized by specific antiserum indicating that occur antigenic similarity among cytotoxins produced by these strains. The toxicity assays on plants showed that the culture supernatants did not provoke any visible morphological change and did not affect their growth. By contrast, the plants treated with bacterial suspension showed disease symptom, such as shriveling and decay of stores bulbus in onion and lettuce plantlets. In conclusion, this study show that phytopathogenic and entomopathogenic S. marcescens may produce a cytototoxin similar to that produced by clinical isolates and it is toxic to different mammalian cell lines. These results are especially important for studies involving this bacterium as biological control agent.
Subject: Animals
Antibodies, Bacterial
Cho Cells
Carcinoma, Squamous Cell
Cell Line, Tumor
Cercopithecus Aethiops
Cricetinae
Cricetulus
Cytotoxins
Female
Humans
Infant
Laryngeal Neoplasms
Lettuce
Moths
Neutralization Tests
Onions
Plant Diseases
Rabbits
Serratia Marcescens
Vero Cells
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/17061504
Date Issue: -1-Uns- -1
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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