Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194791
Type: Artigo de periódico
Title: Role Of Tamm-horsfall Protein In The Binding And In Vivo Phagocytosis Of Type 1 Fimbriated Escherichia Coli By Mouse Peritoneal Macrophages.
Author: Bastos, A C
Santos, L B
Tamashiro, W M
Yamada, A T
Oliveira, U M
Yano, T
Abstract: Tamm-Horsfall glycoprotein (THP) contains manno-oligosaccharides that are recognized by type 1 fimbriae (F1) of Escherichia coli. In the present study, we examined the in vivo phagocytic activity of mouse peritoneal macrophages after treatment of bacteria with THP. At low THP concentrations (12.5 microg/ml and 50 microg/ml) no significant difference was observed in the phagocytosis of E. coli F1+. However, at high THP concentrations (500 microg/ml and 1250 microg/ml) we obtained a reduction of bacterial phagocytosis by mouse peritoneal macrophages.
Subject: Adjuvants, Immunologic
Animals
Blotting, Western
Electrophoresis, Polyacrylamide Gel
Escherichia Coli
Female
Fimbriae, Bacterial
Humans
Macrophages, Peritoneal
Mice
Mice, Inbred Balb C
Mucoproteins
Phagocytosis
Uromodulin
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/11449310
Date Issue: 2001
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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