Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194747
Type: Artigo de periódico
Title: Clinical Relevance And Virulence Factors Of Pigmented Serratia Marcescens.
Author: Carbonell, G V
Della Colleta, H H
Yano, T
Darini, A L
Levy, C E
Fonseca, B A
Abstract: Pigmented Serratia marcescens isolated in a Brazilian hospital were studied with respect to frequency of isolation, serotyping, antibiotic resistance and virulence factors. The serotype most frequent was O6:K14 (53%) and all isolates were resistant to ampicillin, cephalothin and tetracycline. The majority of the isolates (92%) were resistant to the action of human serum and all produced cytotoxins on Vero, CHO, HEp-2 and HeLa cells. These isolates were virulent for mice (LD(50)=10(7) bacteria ml(-1)) and showed virulence factors, but were isolated with low frequency (3. 4%) and caused infection in only 31% of cases. Analysis of serotyping, phage typing and chromosomal DNA revealed at least 13 unrelated strains among pigmented S. marcescens. In conclusion, this work describes a low frequency of isolation of pigmented S. marcescens from clinical specimens, indicating that non-pigmented strains are clinically more significant.
Subject: Animals
Anti-bacterial Agents
Brazil
Cho Cells
Cercopithecus Aethiops
Cricetinae
Cross Infection
Cytotoxins
Electrophoresis, Gel, Pulsed-field
Female
Hela Cells
Humans
Mice
Plasmids
Respiratory Tract Infections
Serotyping
Serratia Infections
Serratia Marcescens
Vero Cells
Virulence
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/10799805
Date Issue: 2000
Appears in Collections:Unicamp - Artigos e Outros Documentos

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