Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194594
Type: Artigo de periódico
Title: [cerebral Hemometabolism: Variability In The Acute Phase Of Traumatic Coma].
Author: Falcão, A L
Araújo, S
Dragosavac, D
Terzi, R G
Thiesen, R A
Cintra, E A
Sardinha, L A
Capone Neto, A
Dantas Filho, V P
Quagliato, E M
Abstract: to evaluate the interrelationships between cerebral and systemic hemometabolic alterations in patients with severe traumatic brain injury managed according to a standardized therapeutic protocol. prospective, interventional study in patients with traumatic coma. a general Intensive Care Unit in a teaching hospital. twenty-seven patients (21M e 6F), aging 14 - 58 years, with severe acute brain trauma, presenting with three to eight points on the Glasgow Coma Scale, were prospectively evaluated according to a cumulative protocol for the management of acute intracranial hypertension, where intracranial pressure (ICP) and cerebral extraction of oxygen (CEO2) were routinely measured. Hemometabolic interrelationships involving mean arterial pressure (MAP), ICP, arterial carbon dioxide tension (PaCO2), CEO2, cerebral perfusion pressure (CPP) and systemic extraction of oxygen (SEO2) were analyzed. routine therapeutic procedures. no correlation was found between CEO2 and CPP (r = -0.07; p = 0.41). There was a significant negative correlation between PaCO2 and CEO2 (r = -0.24; p = 0.005) and a positive correlation between SEO2 and CEO2 (r = 0.24; p = 0.01). The mortality rate in this group of patients was 25.9% (7/27). 1) CPP and CEO2 are unrelated; 2) CEO2 and PaCO2 are closely related; 3) during optimized hyperventilation, CEO2 and SEO2 are coupled.
Subject: Adolescent
Adult
Blood Pressure
Brain
Brain Injuries
Carbon Dioxide
Cerebrovascular Circulation
Clinical Protocols
Coma
Female
Humans
Hyperventilation
Intracranial Pressure
Male
Middle Aged
Oxygen
Partial Pressure
Prospective Studies
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/11018825
Date Issue: 2000
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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