Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: First Total Synthesis Of Aspinolide B, A New Pentaketide Produced By Aspergillus Ochraceus.
Author: Pilli, R A
Victor, M M
de Meijere, A
Abstract: The first asymmetric total synthesis of Aspinolide B (1), a new 10-membered lactone discovered by chemical screening methods in the cultures of Aspergillus ochraceus, has been accomplished. The key steps included a selective Felkin-type addition of TMS-acetylene to aldehyde 3a and a Nozaki-Hiyama-Kishi coupling reaction to build the required 10-membered ring. This synthesis confirmed the absolute stereochemistry of aspinolide B, established through Helmchen's method and corrected its previously reported specific optical rotation.
Subject: Aspergillus Ochraceus
Chromatography, Gas
Optical Rotation
Rights: fechado
Identifier DOI: 
Date Issue: 2000
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File SizeFormat 
pmed_10987921.pdf272.06 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.