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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.title[isoniazid-induced Hepatic Failure. Report Of A Case].pt_BR
dc.contributor.authorPereira, R Mpt_BR
dc.contributor.authorTresoldi, A Tpt_BR
dc.contributor.authorHessel, Gpt_BR
unicamp.authorR M Pereira, Departamento de Pediatria da Faculdade de Ciências Médicas, Universidade Estadual de Campinas. rmpereira@uol.com.brpt_BR
unicamp.author.externalA T Tresoldi,pt
unicamp.author.externalG Hessel,pt
dc.subjectAntitubercular Agentspt_BR
dc.subjectDrug Therapy, Combinationpt_BR
dc.subjectDrug-induced Liver Injurypt_BR
dc.subjectHumanspt_BR
dc.subjectInfantpt_BR
dc.subjectIsoniazidpt_BR
dc.subjectLiver Failure, Acutept_BR
dc.subjectMalept_BR
dc.subjectPyrazinamidept_BR
dc.subjectRifampinpt_BR
dc.subjectTuberculosis, Meningealpt_BR
dc.subjectTuberculosis, Pulmonarypt_BR
dc.description.abstractIsoniazid and pyrazinamide are both well-known hepatotoxic drugs. When isoniazid is used, the hepatic lesion appears before than when pyrazinamide is used. This paper intends to relate a case of a 5-month-old patient who had lungs' and meningeal tuberculosis and who developed toxic hepatitis accomplished by hepatic failure while he was being treated with isoniazid, pyrazinamide and rifampicin. The clinic manifestations and the laboratory alterations were detected in the fifth day of treatment and the recovery was fast; and almost complete by the end of the first week, in which the use of isoniazid had been suspended. Although it was necessary to take the patient to the intensive care unit, he had a good recovery, without sequels.en
dc.relation.ispartofArquivos De Gastroenterologiapt_BR
dc.relation.ispartofabbreviationArq Gastroenterolpt_BR
dc.date.issuedpt_BR
dc.identifier.citationArquivos De Gastroenterologia. v. 37, n. 1, p. 72-5pt_BR
dc.language.isoporpt_BR
dc.description.volume37pt_BR
dc.description.firstpage72-5pt_BR
dc.rightsabertopt_BR
dc.rights.holderpt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0004-2803pt_BR
dc.identifier.doipt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/10962632pt_BR
dc.date.available2015-11-27T12:22:38Z-
dc.date.accessioned2015-11-27T12:22:38Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:22:38Z (GMT). No. of bitstreams: 1 pmed_10962632.pdf: 158586 bytes, checksum: 439b73f25bd560bf7335fec45c8adaeb (MD5) Previous issue date: nullen
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194568-
dc.identifier.idPubmed10962632pt_BR
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