Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194488
Type: Artigo de periódico
Title: [the Experimental Infection Of Cebus Apella Sp. Monkeys With Trypanosoma Cruzi. Its Clinical, Electrocardiographic And Anatomicopathological Assessment].
Author: de Almeida, E A
Navarro, M R
Guariento, M E
Carvalhal, S dos S
Abstract: Thirty-two monkeys were captured and adapted to laboratory conditions captives isolated. They were submitted to multiple xenodiagnosis which were negative. Twelve were infected intraperitoneally with different strains of T. cruzi (1.10(5) to 5.10(6)). Twenty were the control group. Between on to six years both the control group and the infected monkeys, were submitted to xenodiagnosis, serological testing clinical examination and electrocardiography. The clinical examination and the electrocardiogram were always normal. The monkey were autopsied and histological examination detected in the infected group four monkeys with evidence of disease: one with parasites in the tissue and three with chronic myocarditis. Parasitaemia was in 66.66% of the monkeys in the acute phase and the serology was positive in 91.66% in the chronic phase. The authors concluded that Cebus monkeys were not susceptible to the development of the disease but they could be utilized to maintain of such strains and studies of serological research in long-terms infections.
Subject: Animals
Cebus
Chagas Disease
Disease Models, Animal
Electrocardiography
Female
Male
Monkey Diseases
Time Factors
Trypanosoma Cruzi
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/1308068
Date Issue: -1-Uns- -1
Appears in Collections:Unicamp - Artigos e Outros Documentos

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