Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194483
Type: Artigo de periódico
Title: [magnetic Resonance Imaging And Clinical Features In Adults With Monophasic Demyelinating Disease. Acute Disseminated Encephalomyelitis Or A Variant Of Multiple Sclerosis?].
Author: Reis, F
Kobayashi, E
Maciel, E P
Zanardi, V de A
Netto, J R
Damasceno, B P
Cendes, F
Abstract: Acute disseminated encephalomyelitis (ADEM) is a widespread monophasic inflammatory disease affecting the central nervous system, that usually follows an infection or vaccination. In this study, we present an analysis of magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) and clinical aspects in four patients with clinical diagnosis of ADEM. The presence of MRI demyelinating lesions was crucial, but not in itself sufficient for definitive diagnosis. Clinical and MRI follow up, in order to exclude new lesions and to reevaluate the former ones, as well as CSF, were important for the differential diagnosis with other demyelinating diseases, particularly multiple sclerosis. In addition, we have shown that early treatment with methylprednisolone after the initial symptoms was effective for improving clinical manifestations as well as for reducing MRI lesions.
Subject: Acute Disease
Adult
Demyelinating Diseases
Diagnosis, Differential
Encephalomyelitis, Acute Disseminated
Glucocorticoids
Humans
Magnetic Resonance Imaging
Male
Methylprednisolone
Multiple Sclerosis
Retrospective Studies
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/10751923
Date Issue: 1999
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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