Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194283
Type: Artigo de periódico
Title: [an Exploratory Study Of The Association Between Lipid Profile And Bone Mineral Density In Menopausal Women In A Campinas Reference Hospital].
Author: Zabaglia, S F
Pedro, A O
Pinto Neto, A M
Guarisi, T
Paiva, L H
Lane, E
Abstract: A total of 72 postmenopausal patients presenting no risk factors for cardiovascular disease nor osteoporosis, were studied. The study evaluated total serum cholesterol and fractions and bone mass by densitometry of the lumbar spine and femur using a Lunar-DPX. There was no association between lipid profile variables and bone mineral density, except for high density lipoprotein (HDL), which showed an inverse correlation (p=0.001). Multiple regression showed that total cholesterol levels higher than 240 mg% had a positive association with BMD (p=0.026). In addition, the ratio between LDL and HDL (Castelli 2 index) showed a negative association with BMD (p=0.002). The diagnostic validation test showed that all lipid profile variables had low sensitivity and specificity as indicators for osteoporosis. The conclusions were that lipid profile variables did not show a significant association with bone mass and could not be used as indicators for bone mineral density.
Subject: Adult
Aged
Analysis Of Variance
Bone Density
Brazil
Female
Humans
Lipids
Menopause
Middle Aged
Osteoporosis, Postmenopausal
Roc Curve
Regression Analysis
Sensitivity And Specificity
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/9878910
Date Issue: -1-Uns- -1
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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