Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194242
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.title[measuring Cyclosporine Levels In Whole Blood In Kidney Transplantation].pt_BR
dc.contributor.authorBottini, P Vpt_BR
dc.contributor.authorAlves-Cunha, F Apt_BR
dc.contributor.authorModa, M Apt_BR
dc.contributor.authorSouza, M Ipt_BR
dc.contributor.authorGarlipp, C Rpt_BR
unicamp.authorP V Bottini, Departamento de Patologia Clínica, Faculdade de Ciências Médicas, UNICAMP, Campinas, SP.pt_BR
unicamp.author.externalF A Alves-Cunha,pt
unicamp.author.externalM A Moda,pt
unicamp.author.externalM I Souza,pt
unicamp.author.externalC R Garlipp,pt
dc.subjectCyclosporinept_BR
dc.subjectFemalept_BR
dc.subjectFluorescence Polarization Immunoassaypt_BR
dc.subjectHumanspt_BR
dc.subjectImmunosuppressive Agentspt_BR
dc.subjectKidney Transplantationpt_BR
dc.subjectMalept_BR
dc.subjectRadioimmunoassaypt_BR
dc.subjectRegression Analysispt_BR
dc.subjectReproducibility Of Resultspt_BR
dc.description.abstractCyclosporin A is a potent immunosuppressive drug effective in combatting rejection following organ transplantation. In na effort to replace a radioimmunoassay (RIA) for whole blood determination of cyclosporine (Cya) we compared RIA with fluorescence polarization immunoassay (FPIAm). 65 blood samples were analysed from kidney transplanted patients. The samples were collected into tubes containing EDTA as anticoagulant and analysed by RIA and FPIAm. The statistical analysis revealed a difference between both methods (p < 0.05). The linear-regression comparison of Cya concentration measured by RIA and FPIAm showed the following relationship: Cya(FPIAm) = 1.06 x Cya(RIA) + 5.8 (r = 0.9817). We conclude that FPIAm provides na alternative method for measuring cyclosporine in whole blood with the added advantages of being reasonably rapid, precise and easy to perform.en
dc.relation.ispartofRevista Da Associação Médica Brasileira (1992)pt_BR
dc.relation.ispartofabbreviationRev Assoc Med Braspt_BR
dc.date.issuedpt_BR
dc.identifier.citationRevista Da Associação Médica Brasileira (1992). v. 44, n. 3, p. 176-8pt_BR
dc.language.isoporpt_BR
dc.description.volume44pt_BR
dc.description.firstpage176-8pt_BR
dc.rightsfechadopt_BR
dc.rights.holderpt_BR
dc.sourcePubMedpt_BR
dc.identifier.issn0104-4230pt_BR
dc.identifier.doipt_BR
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pubmed/9755544pt_BR
dc.date.available2015-11-27T12:19:22Z-
dc.date.accessioned2015-11-27T12:19:22Z-
dc.description.provenanceMade available in DSpace on 2015-11-27T12:19:22Z (GMT). No. of bitstreams: 0 Previous issue date: nullen
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194242-
dc.identifier.idPubmed9755544pt_BR
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.