Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194159
Type: Artigo de periódico
Title: Fatty Acid-mediated Uncoupling Of Potato Tuber Mitochondria.
Author: Saviani, E E
Martins, I S
Abstract: The present work examined whether the ATP/ADP carrier, other than the plant uncoupling mitochondrial protein, participates in free fatty acid-mediated uncoupling of potato tuber mitochondria. The basal respiration rate of succinate-energized mitochondria was stimulated by a low concentration of palmitate (20 microM). This uncoupling was reversed by 10 microM carboxyatractyloside and by the subsequent addition of 0.1% bovine serum albumin. The decrease in membrane potential caused by palmitate was suppressed by carboxyatractyloside (1 microM) and, to a lesser degree, by bongkrekate (20 microM). GTP could also reversed this decrease via a carboxyatractyloside-independent mechanism. These results indicate that the ATP/ADP carrier, along with the plant uncoupling mitochondrial protein, participates in the protonophoric action of palmitate in potato tuber mitochondria.
Subject: Atractyloside
Carrier Proteins
Fatty Acids, Nonesterified
Intracellular Membranes
Ion Channels
Membrane Potentials
Membrane Proteins
Mitochondria
Mitochondrial Proteins
Oxygen Consumption
Palmitates
Plant Proteins
Receptors, Cytoplasmic And Nuclear
Serum Albumin, Bovine
Solanum Tuberosum
Succinates
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/9584997
Date Issue: 1998
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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