Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/194036
Type: Artigo de periódico
Title: Multidimensional Assessment Of Motor Function In A Child With Cerebral Palsy Following Intrathecal Administration Of Baclofen.
Author: Almeida, G L
Campbell, S K
Girolami, G L
Penn, R D
Corcos, D M
Abstract: This case report describes an 11-year-old boy with spastic diplegia whose reflex status, range of motion (ROM), strength, and motor performance were measured before and after implantation of an indwelling system for delivery of intrathecally administered baclofen. Before baclofen use, the subject experienced clonus that interfered with walking, needed assistance with transfers, and was unable to independently put on underwear and socks. Measures of spasticity, kinematics and electromyographic activity during voluntary movements, ROM, Gross Motor Function Measure (GMFM) scores, and self-reports of change were obtained at baseline, before and after bolus baclofen injection, during a double-blind placebo-controlled clinical trial of baclofen administration via an indwelling pump, and after 1 and 2 years of baclofen therapy. Spasticity, Babinski reflexes, clonus, strength, and coactivation of antagonist muscles during voluntary movement were decreased shortly after baclofen administration began. Hip and ankle ROM increased, upper-extremity movement speed increased, independence in dressing and transfers improved, and orthoses were discarded. After 1 and 2 years, GMFM scores were 7.8% and 6.4% above baseline, respectively; the subject won a fitness award. After 2 years, ROM was worse than at baseline and concerns regarding hip subluxation arose. Single-joint movement control and independence improved and spasticity decreased during baclofen administration.
Subject: Activities Of Daily Living
Baclofen
Cerebral Palsy
Child
Double-blind Method
Electromyography
Humans
Injections, Spinal
Male
Motor Skills
Muscle Relaxants, Central
Range Of Motion, Articular
Time Factors
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/9225847
Date Issue: 1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

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