Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/193945
Type: Artigo de periódico
Title: Isolation Of Protein Factors From Opossum (didelphis Albiventris) Serum Which Protect Against Bothrops Jararaca Venom.
Author: Farah, M F
One, M
Novello, J C
Toyama, M H
Perales, J
Moussatché, H
Domont, G B
Oliveira, B
Marangoni, S
Abstract: The fractionation of Didelphis albiventris serum by DEAE-Sephadex A50 yields a fraction (DA2) which protects the opossum against Bothrops venom. One polypeptide (DA2-II) responsible for this protection was isolated from fraction DA2 by ion exchange chromatography and biochemically characterized. DA2-II is a 43,000 mol. wt glycoprotein with the following N-terminal sequence: LKAMDTTPPLKIKKEPVK. Pairwise comparison of the amino acid sequence with four anti-hemorrhagic factors isolated from other opossum species indicated that DA2-II possesses high similarity (60-80%) with these proteins.
Subject: Amino Acid Sequence
Animals
Antivenins
Blood Proteins
Bothrops
Chemical Fractionation
Chromatography, Ion Exchange
Crotalid Venoms
Electrophoresis, Polyacrylamide Gel
Molecular Sequence Data
Molecular Weight
Opossums
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/8896201
Date Issue: 1996
Appears in Collections:Unicamp - Artigos e Outros Documentos

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