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|Type:||Artigo de periódico|
|Title:||Evaluation Of Recent Techniques For Detection Of Red Blood Cell Antibodies In Sera Of Reference Samples, Patients, Pregnant Women, And Blood Donors.|
|Author:||de Castilho, L M|
Bechelli, A P
Le Pennec, P Y
Mendes, N F
|Abstract:||The sensitivity of the low ionic strength solution antiglobulin test (LISS-AGT), polyethylene glycol antiglobulin test (PEG-AGT), low ionic strength solution solid-phase antiglobulin test (LISS-SPAT), gel low ionic strength solution antiglobulin test (GEL-LISS), and gel papain test (GEL-PAP) was compared in titration studies of 460 sera containing identified IgG alloantibodies. The GEL-PAP was 100% sensitive to detect Rh antibodies, whereas the PEG-AGT was the most sensitive to detect Kell, Duffy, Kidd, Ss, and rare blood group antibodies. The better performance of PEG-AGT was especially obvious with Kell, Duffy, and Ss antibodies (S = 100%). When the sensitivity of the LISS-AGT, PEG-AGT, GEL-LISS, and GEL-PAP was evaluated in different routines, the GEL-LISS showed to be more sensitive than PEG-AGT in the detection of clinically significant antibodies. These discrepant results showed that the performance of a technique may change when it is applied as a routine.|
Sensitivity And Specificity
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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