Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/193713
Type: Artigo de periódico
Title: Local Reaction And Migration Of Injected Silicone Gel: Experimental Study.
Author: do Amaral, C M
Tiziani, V
Cintra, M L
Amstalden, I
Palhares, F B
Abstract: A study of the local and migratory effects of free silicone gel taken from a mammary prosthesis is reported. Thirty eight Wistar rats were injected in their subcutaneous space with 1 cm3 of silicone gel. The animals were sacrificed on day: 3, 7, 15, 30, 60, 180, 240, 360, 420, 450. The visceral organs (heart, kidneys, lungs, stomach, gonads, liver, pancreas, spleen, intestine), as well as the tissue adjacent to the region of injection, were histologically analyzed. There was no detectable silicone and no damage to the visceral organs based on routine histopathological analysis. The greatest fibrosis was observed at the extremities of the disk formed by the silicone in the subcutaneous space.
Subject: Animals
Connective Tissue
Female
Fibrosis
Foreign-body Migration
Foreign-body Reaction
Gels
Giant Cells, Foreign-body
Injections, Subcutaneous
Male
Mammaplasty
Prostheses And Implants
Rats
Rats, Wistar
Silicones
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/8273537
Date Issue: 1993
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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