Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/193677
Type: Artigo de periódico
Title: [post-transfusional Hepatitis In The City Of Campinas, Sp, Brazil. Ii. Presence Of Anti-hbc And Anti-hcv Antibodies In Blood Donor Candidates And Occurrence Of Post-transfusional Hepatitis C In Recipients Of Blood Or Derivates].
Author: Gonçales Júnior, F L
Pedro, R de J
da Silva, L J
Boccato, R S
Gonçales, N S
Abstract: We have analysed anti-HBc and anti-HCV antibodies in serum samples from 799 donors which had their blood or derivates transfused to 111 recipients. Anti-HBc and anti-HCV were reactive in respectively 9 and 2.1% of the donors tested. We have observed that among the 111 recipients, 44 had received at least one positive anti-HBc unit and 67 had been transfused only with negative anti-HBc, units. The risk of developing hepatitis C virus was 4.5 times higher for the recipients who received at least one positive anti-HBc unit. If the test for anti-HBc had been made for the blood donors in the serological screening, about 56% of the HCV cases in the recipients could have been avoided. The population of recipients who received at least one reacting unit of anti-HCV, presented a risk 29 times higher of developing this hepatitis, as compared to the transfused recipients with all anti-HCV negative units. Testing blood from donors for anti-HCV would avoid 79% of the post-transfusional HCV cases. Brazilian candidates to blood donors seem to be carriers either simultaneously or sequentially to hepatitis virus B and C, since 44.4% of the positive anti-HCV were also positive for anti-HBc. Testing for anti-HBc and anti-HCV in blood screening must be indicated in order to prevent post-transfusional hepatitis transmission in our community.
Subject: Blood Donors
Blood Transfusion
Brazil
Hepacivirus
Hepatitis Antibodies
Hepatitis B Core Antigens
Hepatitis C
Hepatitis C Antibodies
Humans
Prospective Studies
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/7506447
Date Issue: -1-Uns- -1
Appears in Collections:Unicamp - Artigos e Outros Documentos

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