Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/193676
Type: Artigo de periódico
Title: [post-transfusional Hepatitis In The City Of Campinas, Sp, Brazil. I. Incidence, Etiological Agents And Clinico-epidemiological Aspects Of Hepatitis C].
Author: Gonçales Júnior, F L
Pedro, R de J
da Silva, L J
Boccato, R S
Ramos, M C
Gonçales, N S
Abstract: We have followed up 111 transfusion receptors in the ambulatory, for at least 180 days, in order to evaluate the occurrence of post-transfusional hepatitis and the etiological agents involved in the disease in the city of Campinas, state of São Paulo, Brazil. At the end of the study we have diagnosed this hepatitis in 18 (16.2%) subjects. Out of these 18 subjects, 16 (89%) were caused by hepatitis C virus, 1 (5.5%) caused by hepatitis B virus and 1 (5.5%) with undetermined etiology, 15 months after transfusion. The average incubation period of HCV was 71 days and 23% of the HCV positive receptors remained with increased AST/ALT for more than 6 months. Late serum conversion was observed for anti-HCV in 71.4% of the subjects, averaging 135 days after the transfusion. An ALT dosage and anti-HCV determination, 3 and 6 months after transfusion would diagnose, respectively, 71 and 93% of the cases which developed post-transfusional HCV.
Subject: Adolescent
Adult
Aged
Alanine Transaminase
Blood Transfusion
Brazil
Female
Follow-up Studies
Hepacivirus
Hepatitis Antibodies
Hepatitis C
Hepatitis C Antibodies
Humans
Male
Middle Aged
Rights: aberto
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/7506446
Date Issue: -1-Uns- -1
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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