Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/193656
Type: Artigo de periódico
Title: Alterations To The Permeability Of Plant And Animal Mitochondria Submitted To Ca2+ Releasing Agents.
Author: Morselli, A L
Pereira-Da-Silva, L
Abstract: 1. Mitochondria from different rat tissues and from plants were compared as regards their sensitivity towards Ca2+ in the presence of different Ca2+ releasing agents, and the phospholipase A2 activity was evaluated in the different mitochondrial preparations. 2. The mitochondria were exposed to Ca2+ and an oxidant such as t-butylhydroperoxide or diamide or to Ca2+ and inorganic phosphate, and plant mitochondria were seen to be much more resistant than liver, brain or kidney mitochondria of rats to the deleterious effects of these agents. 3. The phospholipase A2 activity is not directly involved in the alterations of the mitochondrial inner membrane permeability within the first 10 min of incubation under our experimental conditions. 4. The protection conferred by ATP and Mg2+ against Ca2+ efflux from mitochondria or the decrease in the mitochondrial transmembrane electrical potential was also observed under our experimental conditions, but cannot be attributed to an enhancement of the reacylation of lysophospholipids resulting from the phospholipase A2 activity.
Subject: Adenosine Triphosphate
Animals
Calcium
Diamide
Female
In Vitro Techniques
Magnesium
Membrane Potentials
Mitochondria
Permeability
Peroxides
Phosphates
Phospholipases A
Phospholipases A2
Plants
Rats
Rats, Wistar
Species Specificity
Tert-butylhydroperoxide
Rights: fechado
Identifier DOI: 
Address: http://www.ncbi.nlm.nih.gov/pubmed/1458833
Date Issue: 1992
Appears in Collections:Unicamp - Artigos e Outros Documentos

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