Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/149
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.type.categoryoriginal articlept_BR
dc.type.versionpublishedVersionpt_BR
dc.titleQuimioterapia da doença de Chagas: estado da arte e perspectivas no desenvolvimento de novos fármacospt_BR
dc.title.alternativeChemotherapy of Chagas' disease: state of the art and perspectives for the development of new drugsen
dc.contributor.authorDIAS, Luiz C.pt_BR
dc.contributor.authorDESSOY, Marco A.pt_BR
dc.contributor.authorSILVA, Jean Jerley N.pt_BR
dc.contributor.authorTHIEMANN, Otavio H.pt_BR
dc.contributor.authorOLIVA, Glauciuspt_BR
dc.contributor.authorANDRICOPULO, Adriano D.pt_BR
unicamp.authorDIAS, Luiz C.:Universidade Estadual de Campinas, Instituto de Química, Departamento de Química Orgânicapt_BR
unicamp.author.externalDESSOY, Marco A.pt
unicamp.author.externalSILVA, Jean Jerley N.pt
unicamp.author.externalTHIEMANN, Otavio H.pt
unicamp.author.externalOLIVA, Glauciuspt
unicamp.author.externalANDRICOPULO, Adriano D.pt
dc.subjectChagas' diseasept_BR
dc.subjectEnzymespt_BR
dc.subjectInhibitorspt_BR
dc.description.abstractNeglected diseases are a major global cause of illness, long-term disability and death. Chagas' disease is a parasitic infection widely distributed throughout Latin America, with devastating consequences in terms of human morbidity and mortality. The existing drug therapy suffers from a combination of drawbacks including poor efficacy, resistance and serious side effects. In 2009, we celebrate the 100th anniversary of the discovery of Chagas' disease, facing the challenges of developing new, safe and effective drugs for the treatment of this disease. This brief review attempts to highlight the state of the art, limitations and perspectives of Chagas' disease drug development.en
dc.relation.ispartofQuímica Novapt_BR
dc.publisher.countryBrasilpt_BR
dc.publisherSociedade Brasileira de Químicapt_BR
dc.date.issued2009pt_BR
dc.identifier.citationQuímica Nova, v.32, n.9, p.2444-2457, 2009pt_BR
dc.language.isoporpt_BR
dc.description.volume32pt_BR
dc.description.issuenumber9pt_BR
dc.description.firstpage2444pt_BR
dc.description.lastpage2457pt_BR
dc.rightsabertopt_BR
dc.rights.holderCopyright Sociedade Brasileira de Químicapt_BR
dc.sourceSciELOpt_BR
unicamp.cruespUSPpt_BR
dc.identifier.issn0100-4042pt_BR
dc.identifier.doi10.1590/S0100-40422009000900038pt_BR
dc.identifier.urlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000900038pt_BR
dc.identifier.urlhttp://www.scielo.br/pdf/qn/v32n9/v32n9a38.pdfpt_BR
dc.description.sponsorshipWHO World Health Organization - Organização Mundial de Saúdept_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorremissiveCNPq_Brasilpt_BR
dc.description.sponsorremissiveFAPESP_Brasilpt_BR
dc.description.sponsorremissiveWHOpt_BR
dc.date.available2013-07-26T17:56:17Z
dc.date.available2016-07-01T12:55:27Z-
dc.date.accessioned2013-07-26T17:56:17Z
dc.date.accessioned2016-07-01T12:55:27Z-
dc.description.provenanceMade available in DSpace on 2013-07-26T17:56:17Z (GMT). No. of bitstreams: 2 art_DESSOY_Quimioterapia_da_doenca_de_Chagas_estado_da_2009.pdf.txt: 90038 bytes, checksum: 34fd2758917ab7398f2a3c7e2974d2b7 (MD5) art_DESSOY_Quimioterapia_da_doenca_de_Chagas_estado_da_2009.pdf: 1995336 bytes, checksum: 3389e7ef87e70c6b17ff17f3719c7d6b (MD5) Previous issue date: 2009en
dc.description.provenanceMade available in DSpace on 2016-07-01T12:55:27Z (GMT). No. of bitstreams: 2 art_DESSOY_Quimioterapia_da_doenca_de_Chagas_estado_da_2009.pdf.txt: 90038 bytes, checksum: 34fd2758917ab7398f2a3c7e2974d2b7 (MD5) art_DESSOY_Quimioterapia_da_doenca_de_Chagas_estado_da_2009.pdf: 1995336 bytes, checksum: 3389e7ef87e70c6b17ff17f3719c7d6b (MD5) Previous issue date: 2009en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/149
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/149-
dc.contributor.departmentQuímica Orgânica
dc.contributor.unidadeIQpt
Appears in Collections:IQ - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
art_DESSOY_Quimioterapia_da_doenca_de_Chagas_estado_da_2009.pdfpublished version1.95 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.