Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/1142
Type: Artigo de periódico
Title: Alkaloids from the Bark of Guatteria hispida and Their Evaluation as Antioxidant and Antimicrobial Agents
Author: COSTA, Emmanoel Vilaca
PINHEIRO, Maria Lucia B.
BARISON, Andersson
CAMPOS, Francinete R.
SALVADOR, Marcos J.
MAIA, Beatriz Helena L. N. S.
CABRAL, Elaine C.
EBERLIN, Marcos N.
Abstract: Phytochemical investigation of the bark of Guatteria hispida afforded three new alkaloids, 9-methoxy-O-methylmoschatoline (1), 9-methoxyisomoschatoline (2), and isocerasonine (3), along with 10 known alkaloids, 8-oxopseudopalmatine (4), O-methylmoschatoline (5), lysicamine (6), liriodenine (7), 10-methoxyliriodenine (8), nornuciferine (9), anonaine (10), xylopine (11), coreximine (12), and isocoreximine (13). The major compounds, 2, 6, 12, and 13, showed significant antioxidant capacity in the ORAC(FL), assay. Compounds 5, 6, and 7 were active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 mu g mL(-1).
Country: Estados Unidos
Editor: AMER CHEMICAL SOC
Citation: JOURNAL OF NATURAL PRODUCTS, v.73, n.6, p.1180-1183, 2010
Rights: fechado
Identifier DOI: 10.1021/np100013r
Address: http://dx.doi.org/10.1021/np100013r
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Date Issue: 2010
Appears in Collections:IB - Artigos e Materiais de Revistas Científicas

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