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|Type:||Artigo de periódico|
|Title:||A Reliable Ex Vivo Invasion Assay Of Human Reticulocytes By Plasmodium Vivax|
|Abstract:||Currently, there are no reliable RBC invasion assays to guide the discovery of vaccines against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America. Here we describe a protocol for an ex vivo P vivax invasion assay that can be easily deployed in laboratories located in endemic countries. The assay is based on mixing enriched cord blood reticulocytes with matured, trypsin-treated P vivax schizonts concentrated from clinical isolates. The reliability of this assay was demonstrated using a large panel of P vivax isolates freshly collected from patients in Thailand. © 2011 by The American Society of Hematology.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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