Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/108375
Type: Artigo de periódico
Title: Levothyroxine And The Problem Of Interchangeability Of Drugs With Narrow Therapeutic Index [levotiroxina E O Problema Da Permutabilidade De Drogas De Estreito Intervalo Terapêutico]
Author: Ward L.S.
Abstract: The exchange of a prescribed drug by other similar, by generic products and even by custom products has become common practice in our country, often ignoring basic tenets of bioequivalence, interchangeability, stability and characteristics of the pharmaceutical compounds. In the case of drugs of narrow therapeutic index, such as levothyroxine, these problems are intensified, putting the effectiveness of treatment and patient health at serious risk. We review the pertinent legislation, emphasizing the characteristics of levothyroxine and adverse effects that limit the interchangeability of the compound. © ABE&M todos os direitos reservados.
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Rights: aberto
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Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-82955189768&partnerID=40&md5=e27edd68dfca59c73a059b9dc3874d2d
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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