Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/108265
Type: Artigo de periódico
Title: The Heck-matsuda Arylation Of 2-hetero-substituted Acrylates
Author: De Azambuja F.
Correia C.R.D.
Abstract: The Heck-Matsuda arylation of 2-aza and 2-oxo-substituted acrylates is described. Several reaction conditions were evaluated including the influence of solvents, temperature, catalysts, and stoichiometry. While the oxygenated system was successfully arylated in benzonitrile with Pd2(dba) 3 as catalyst, the aza-acrylate furnished methoxylated products. The methoxylated products were subjected to an elimination/reduction protocol to obtain the corresponding N,O-protected phenylalanine derivatives. A one-pot procedure for the preparation of phenylalanine derivatives from 2-aza-substituted acrylates is presented. © 2010 Elsevier Ltd. All rights reserved.
Editor: 
Rights: fechado
Identifier DOI: 10.1016/j.tetlet.2010.10.132
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-78649813461&partnerID=40&md5=efeb4d5a509fdb16ce4330dafa40190b
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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