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Type: Capítulo de livro
Title: Behçet's Disease: Symptoms, Diagnosis And Treatment
Author: Postal M.
Appenzeller S.
Abstract: Behçet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown etiology with the clinical features of mucocutaneous lesions, ocular, vascular, articular, gastrointestinal, urogenital, pulmonary, and neurologic involvement. It is believed to be due to an auto-immune process triggered by an infectious or environmental agent in a genetically predisposed individual. HLA-B51 is the most strongly associated risk factor. The disease usually starts around the third decade of life. Mucocutaneous lesions figure prominently in the presentation and diagnosis, and may be considered the hallmarks of BD. Therefore, their recognition may permit earlier diagnosis and treatment. Although, the treatment has become much more effective in recent years, BD is still associated with severe morbidity and considerable mortality. The main aim of the treatment should be the prevention of irreversible organ damage. Therefore, close monitoring, early and appropriate treatment is mandatory to reduce morbidity and mortality. We will review symptoms, diagnosis and the current state of knowledge regarding the therapeutic approaches for BD. © 2011 Nova Science Publishers, Inc. All rights reserved.
Editor: Nova Science Publishers, Inc.
Citation: Autoimmune Disorders: Symptoms, Diagnosis And Treatment. Nova Science Publishers, Inc., v. , n. , p. 229 - 248, 2011.
Rights: fechado
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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